Beilstein J. Org. Chem.2020,16, 39–49, doi:10.3762/bjoc.16.6
, (iii) demonstrate photoswitching of the whole-body toxicity for the dithienylethene-modified peptides in vivo, (iv) re-analyze previous structure–toxicity relationship data, and (v) select promising candidates for potential clinical development.
Keywords: diarylethenephotoswitch; gramicidin S
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Graphical Abstract
Figure 1:
DAE photoswitch and photoswitchable peptides explored in this study. (A) The reversible photoisomer...